Metabolomic changes in polyunsaturated fatty acids and eicosanoids as diagnostic biomarkers in Mycobacterium avium ssp. paratuberculosis (MAP)-inoculated Holstein–Friesian heifers

Metabolomic changes in polyunsaturated fatty acids and eicosanoids as diagnostic biomarkers in Mycobacterium avium ssp. paratuberculosis (MAP)-inoculated Holstein–Friesian heifers

Abstract Mycobacterium avium subspecies paratuberculosis (MAP) is the causative organism of Johne’s disease, a chronic granulomatous enteritis of ruminants. We have previously used naturally MAP-infected heifer calves to document metabolomic changes occurring in MAP infections. Herein, we used exper...

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Bibliographic Details
Main Authors: Emma N. Taylor, Manfred Beckmann, Glyn Hewinson, David Rooke, Luis A. J. Mur, Ad P. Koets
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Veterinary Research
Subjects:
Mycobacterium avium subsp. paratuberculosis
metabolomics
alpha-linoleic acid and linoleic acid metabolism
polyunsaturated fatty acids
eicosanoids
Online Access:https://doi.org/10.1186/s13567-022-01087-0

Internet

https://doi.org/10.1186/s13567-022-01087-0

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