One Cell At a Time (OCAT): a unified framework to integrate and analyze single-cell RNA-seq data

One Cell At a Time (OCAT): a unified framework to integrate and analyze single-cell RNA-seq data

Abstract Integrative analysis of large-scale single-cell RNA sequencing (scRNA-seq) datasets can aggregate complementary biological information from different datasets. However, most existing methods fail to efficiently integrate multiple large-scale scRNA-seq datasets. We propose OCAT, One Cell At...

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Bibliographic Details
Main Authors: Chloe X. Wang, Lin Zhang, Bo Wang
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Genome Biology
Subjects:
Integration
Single-cell RNA-seq
Differential gene expression
Trajectory inference
Pseudotime inference
Online Access:https://doi.org/10.1186/s13059-022-02659-1

Internet

https://doi.org/10.1186/s13059-022-02659-1

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