Development of a Novel Methotrexate-Loaded Nanoemulsion for Rheumatoid Arthritis Treatment with Site-Specific Targeting Subcutaneous Delivery

Development of a Novel Methotrexate-Loaded Nanoemulsion for Rheumatoid Arthritis Treatment with Site-Specific Targeting Subcutaneous Delivery

Rheumatoid arthritis (RA) is a systemic, chronic autoimmune disease that causes disability due to progressive inflammation and destruction of the tissues around the joints. Methotrexate is mainly used to prevent the progression of joint destruction and reduce the deformity. The major challenge in tr...

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Bibliographic Details
Main Authors: Parvathy Suresh, Mounir M. Salem-Bekhit, Hafsa Palathum Veedu, Sultan Alshehri, Sreeja Chandrasekhar Nair, Sarah I. Bukhari, Vidya Viswanad, Ehab I. Taha, Ram Kumar Sahu, Mohammed M. Ghoneim, Ibrahim Elbagory
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Nanomaterials
Subjects:
rheumatoid arthritis
methotrexate
anti-arthritic activity
nanoemulsion
hemocompatibility
MTT assay
Online Access:https://www.mdpi.com/2079-4991/12/8/1299

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https://www.mdpi.com/2079-4991/12/8/1299

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