Aspartyl Protease Inhibitors as Anti-Filarial Drugs

Aspartyl Protease Inhibitors as Anti-Filarial Drugs

The current treatments for lymphatic filariasis and onchocerciasis do not effectively kill the adult parasitic nematodes, allowing these chronic and debilitating diseases to persist in millions of people. Thus, the discovery of new drugs with macrofilaricidal potential to treat these filarial diseas...

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Bibliographic Details
Main Authors: Liana Beld, Hyeim Jung, Christina A. Bulman, Bruce A. Rosa, Peter U. Fischer, James W. Janetka, Sara Lustigman, Judy A. Sakanari, Makedonka Mitreva
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pathogens
Subjects:
Neglected tropical diseases (NTDs)
filarial nematodes
macrofilaricidal
anti-filarial drugs
gastro-intestinal nematodes
<i>Trichuris</i>
Online Access:https://www.mdpi.com/2076-0817/11/6/707

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https://www.mdpi.com/2076-0817/11/6/707

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