Modeling of atrophy size trajectories: variable transformation, prediction and age-of-onset estimation

Modeling of atrophy size trajectories: variable transformation, prediction and age-of-onset estimation

Abstract Background To model the progression of geographic atrophy (GA) in patients with age-related macular degeneration (AMD) by building a suitable statistical regression model for GA size measurements obtained from fundus autofluorescence imaging. Methods Based on theoretical considerations, we...

詳細記述

書誌詳細
主要な著者: Charlotte Behning, Monika Fleckenstein, Maximilian Pfau, Christine Adrion, Lukas Goerdt, Moritz Lindner, Steffen Schmitz-Valckenberg, Frank G Holz, Matthias Schmid
フォーマット: 論文
言語:English
出版事項: BMC 2021-08-01
シリーズ:BMC Medical Research Methodology
主題:
Geographic atrophy
Age-related macular degeneration
Box-Cox transformation
Mixed-effects models
Prediction
Age-of-onset estimation
オンライン･アクセス:https://doi.org/10.1186/s12874-021-01356-0

インターネット

https://doi.org/10.1186/s12874-021-01356-0

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