miR-200c inhibition and catalase accelerate diabetic wound healing

miR-200c inhibition and catalase accelerate diabetic wound healing

Abstract Background Reactive oxygen species (ROS) are increased in diabetic conditions and play a causal role in diabetic foot ulcers (DFU). We previously showed that ROS up-regulate miR-200c expression, that in turns causes apoptosis, senescence, ROS upregulation and nitric oxide decrease, leading...

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Bibliographic Details
Main Authors: Marco D’Agostino, Sara Sileno, Daniela Lulli, Naomi De Luca, Claudia Scarponi, Massimo Teson, Alessio Torcinaro, Francesca De Santa, Corrado Cirielli, Sergio Furgiuele, Chris H. Morrell, Elena Dellambra, Teresa Odorisio, Edward G. Lakatta, Daniele Avitabile, M. C. Capogrossi, Alessandra Magenta
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Biomedical Science
Subjects:
Diabetic foot ulcers
MicroRNAs
Catalase
Skin
Reactive oxygen species
Apoptosis
Online Access:https://doi.org/10.1186/s12929-024-01113-7

Internet

https://doi.org/10.1186/s12929-024-01113-7

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