σE of Streptomyces coelicolor can function both as a direct activator or repressor of transcription
Abstract σ factors are considered as positive regulators of gene expression. Here we reveal the opposite, inhibitory role of these proteins. We used a combination of molecular biology methods and computational modeling to analyze the regulatory activity of the extracytoplasmic σE factor from Strepto...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-01-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-05716-y |