An unbiased, automated platform for scoring dopaminergic neurodegeneration in C. elegans.

Caenorhabditis elegans (C. elegans) has served as a simple model organism to study dopaminergic neurodegeneration, as it enables quantitative analysis of cellular and sub-cellular morphologies in live animals. These isogenic nematodes have a rapid life cycle and transparent body, making high-through...

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Bibliographic Details
Main Authors: Andrew S Clark, Zachary Kalmanson, Katherine Morton, Jessica Hartman, Joel Meyer, Adriana San-Miguel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0281797&type=printable