In Vitro Study of Synergic Effect of Cisplatin and Low Molecular Weight Heparin on Oral Squamous Cell Carcinoma

In Vitro Study of Synergic Effect of Cisplatin and Low Molecular Weight Heparin on Oral Squamous Cell Carcinoma

ObjectivesTo evaluate the possible synergic effect of cisplatin and low molecular weight heparin (LMWH) on oral squamous cell carcinoma (OSCC).Materials and MethodsCisplatin and enoxaparin sodium, alone or in combination, were administered at doses of 1, 2, 4, 8 and 10 µM and 0.1, 0.5, 1, 5, 10, 50,...

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Main Authors: Fabio Camacho-Alonso, T. Gómez-Albentosa, R. E. Oñate-Sánchez, M. R. Tudela-Mulero, M. Sánchez-Siles, Francisco J. Gómez-García, Yolanda Guerrero-Sánchez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
cisplatin
low molecular weight heparin
oral squamous cell carcinoma
enoxaparin sodium
in vitro cell line
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.549412/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.549412/full

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