The 4-α-Glucanotransferase AcbQ Is Involved in Acarbose Modification in <i>Actinoplanes</i> sp. SE50/110

The 4-α-Glucanotransferase AcbQ Is Involved in Acarbose Modification in <i>Actinoplanes</i> sp. SE50/110

The pseudo-tetrasaccharide acarbose, produced by <i>Actinoplanes</i> sp. SE50/110, is a α-glucosidase inhibitor used for treatment of type 2 diabetes patients. In industrial production of acarbose, by-products play a relevant role that complicates the purification of the product and redu...

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Bibliographic Details
Main Authors: Sophia Nölting, Camilla März, Lucas Jacob, Marcus Persicke, Susanne Schneiker-Bekel, Jörn Kalinowski
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Microorganisms
Subjects:
<i>Actinoplanes</i>
acarbose
acarviosyl metabolites
microbial secondary metabolite
acarbose 4-α-glucanotransferase
AcbQ
Online Access:https://www.mdpi.com/2076-2607/11/4/848

Internet

https://www.mdpi.com/2076-2607/11/4/848

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