Macrophages promote pre-metastatic niche formation of breast cancer through aryl hydrocarbon receptor activity

Macrophages promote pre-metastatic niche formation of breast cancer through aryl hydrocarbon receptor activity

Abstract Macrophages that acquire an immunosuppressive phenotype play a crucial role in establishing the pre-metastatic niche (PMN), which is essential for facilitating breast cancer metastasis to distant organs. Our study showed that increased activity of the aryl hydrocarbon receptor (AHR) in lung...

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Bibliographic Details
Main Authors: Xu Jiang, Jiaqi Wang, Liangyu Lin, Liming Du, Yayun Ding, Fanjun Zheng, Hongzhen Xie, Yu Wang, Mingyuan Hu, Benming Liu, Muhan Xu, Jingjie Zhai, Xuefeng Wang, Jiayin Ye, Wei Cao, Chao Feng, Jingyi Feng, Zongliu Hou, Mingyao Meng, Ju Qiu, Qing Li, Yufang Shi, Ying Wang
Format: Article
Language:English
Published: Nature Publishing Group 2024-12-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-024-02042-5

Internet

https://doi.org/10.1038/s41392-024-02042-5

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