Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells

Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells

Abstract Infections in early life can elicit substantially different immune responses and pathogenesis than infections in adulthood. Here, we investigate the consequences of murine cytomegalovirus infection in newborn mice on NK cells. We show that infection severely compromised NK cell maturation a...

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Bibliographic Details
Main Authors: Carmen Rožmanić, Berislav Lisnić, Marina Pribanić Matešić, Andrea Mihalić, Lea Hiršl, Eugene Park, Ana Lesac Brizić, Daniela Indenbirken, Ina Viduka, Marina Šantić, Barbara Adler, Wayne M. Yokoyama, Astrid Krmpotić, Vanda Juranić Lisnić, Stipan Jonjić, Ilija Brizić
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42182-w

Internet

https://doi.org/10.1038/s41467-023-42182-w

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