Tumor site- and stage-specific associations between allelic variants of glutathione S-transferase and DNA-repair genes and overall survival in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy.

INTRODUCTION: Our retrospective cohort study investigated the effect of tumor site and stage on the associations between the allelic variants of glutathione S-transferase (GST) and DNA-repair genes and overall survival (OS) in CRC patients treated with 5-fluorouracil (5-FU)-based adjuvant chemothera...

Full description

Bibliographic Details
Main Authors: Ching-Yu Lai, Ling-Ling Hsieh, Fung-Chang Sung, Reiping Tang, Chyi-Huey Bai, Fang-Yang Wu, Hung-Yi Chiou, Chih-Ching Yeh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720885?pdf=render