Molnupiravir inhibits SARS-CoV-2 variants including Omicron in the hamster model

Molnupiravir inhibits SARS-CoV-2 variants including Omicron in the hamster model

The recent emergence of the SARS-CoV-2 Omicron variant of concern (VOC), which contains a heavily mutated spike protein capable of escaping preexisting immunity, identifies a continued need for interventional measures. Molnupiravir (MK-4482), an orally administered nucleoside analog, has demonstrate...

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Bibliographic Details
Main Authors: Kyle Rosenke, Atsushi Okumura, Matthew C. Lewis, Friederike Feldmann, Kimberly Meade-White, W. Forrest Bohler, Amanda Griffin, Rebecca Rosenke, Carl Shaia, Michael A. Jarvis, Heinz Feldmann
Format: Article
Language:English
Published: American Society for Clinical investigation 2022-07-01
Series:JCI Insight
Subjects:
COVID-19
Virology
Online Access:https://doi.org/10.1172/jci.insight.160108

Internet

https://doi.org/10.1172/jci.insight.160108

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