Major ginsenosides from Panax ginseng promote aerobic cellular respiration and SIRT1-mediated mitochondrial biosynthesis in cardiomyocytes and neurons

Major ginsenosides from Panax ginseng promote aerobic cellular respiration and SIRT1-mediated mitochondrial biosynthesis in cardiomyocytes and neurons

Background: Aerobic cellular respiration provides chemical energy, adenosine triphosphate (ATP), to maintain multiple cellular functions. Sirtuin 1 (SIRT1) can deacetylate peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) to promote mitochondrial biosynthesis. Targeting e...

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Bibliographic Details
Main Authors: Qingxia Huang, Tingting Lou, Jing Lu, Manying Wang, Xuenan Chen, Linyuan Xue, Xiaolei Tang, Wenxiu Qi, Zepeng Zhang, Hang Su, Wenqi Jin, Chenxu Jing, Daqing Zhao, Liwei Sun, Xiangyan Li
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Journal of Ginseng Research
Subjects:
Ginsenosides
Aerobic cellular respiration
Mitochondrial biosynthesis
SIRT1
Cardiomyocytes
Neurons
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845322000239

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http://www.sciencedirect.com/science/article/pii/S1226845322000239

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