Multiphoton In Vivo Microscopy of Embryonic Thrombopoiesis Reveals the Generation of Platelets through Budding

Multiphoton In Vivo Microscopy of Embryonic Thrombopoiesis Reveals the Generation of Platelets through Budding

Platelets are generated by specialized cells called megakaryocytes (MKs). However, MK’s origin and platelet release mode have remained incompletely understood. Here, we established direct visualization of embryonic thrombopoiesis in vivo by combining multiphoton intravital microscopy (MP-IVM) with a...

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Bibliographic Details
Main Authors: Huan Liu, Hellen Ishikawa-Ankerhold, Julia Winterhalter, Michael Lorenz, Mykhailo Vladymyrov, Steffen Massberg, Christian Schulz, Mathias Orban
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cells
Subjects:
megakaryocyte
multiphoton intravital microscopy
thrombopoiesis
yolk sac
fetal liver
c-Myb
Online Access:https://www.mdpi.com/2073-4409/12/19/2411

Internet

https://www.mdpi.com/2073-4409/12/19/2411

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