Three arginine residues in apolipoprotein A-I are critical for activation of lecithin:cholesterol acyltransferase

Three arginine residues in apolipoprotein A-I are critical for activation of lecithin:cholesterol acyltransferase

Previous studies have suggested that the helical repeat formed by residues 143–164 of apolipoprotein A-I (apoA-I) contributes to lecithin:cholesterol acyltransferase (LCAT) activation. To identify specific polar residues involved in this process, we examined residue conservation and topology of apoA...

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Bibliographic Details
Main Authors: Stein Roosbeek, Berlinda Vanloo, Nicolas Duverger, Hans Caster, Joke Breyne, Iris De Beun, Hetal Patel, Joël Vandekerckhove, Carol Shoulders, Maryvonne Rosseneu, Frank Peelman
Format: Article
Language:English
Published: Elsevier 2001-01-01
Series:Journal of Lipid Research
Subjects:
HDL
enzyme
lipoprotein
cholesterol
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520323336

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520323336

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