METTL3‐mediated m6A methylation of TRAF5 inhibits lung adenocarcinoma cell metastasis via activation of the PI3K/AKT/NF‐κB signaling pathway

METTL3‐mediated m6A methylation of TRAF5 inhibits lung adenocarcinoma cell metastasis via activation of the PI3K/AKT/NF‐κB signaling pathway

Abstract Tumor necrosis factor receptor‐associated factor 5 (TRAF5) has been implicated in the pathogenesis of human malignancies. This work aimed to clarify the role of TRAF5 in lung adenocarcinoma (LUAD) progression. Herein, we uncovered that TRAF5 level was reduced in LUAD tissues. Low TRAF5 expr...

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Bibliographic Details
Main Authors: Yu‐Fei Zhou, Jiang‐Tao Li, Qing‐Lin Zheng, Kun‐Lun Ren, Cheng‐Cheng Yi
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
lung adenocarcinoma
m6A
METTL3
PI3K/AKT/NF‐κB
TRAF5
Online Access:https://doi.org/10.1002/kjm2.12791

Internet

https://doi.org/10.1002/kjm2.12791

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