An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model

Abstract The Zika virus (ZIKV) outbreak in the Americas and South Pacific poses a significant burden on human health because of ZIKV’s neurotropic effects in the course of fetal development. Vaccine candidates against ZIKV are coming online, but immunological tools to study anti-ZIKV responses in pr...

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Bibliographic Details
Main Authors: Jasdave S. Chahal, Tao Fang, Andrew W. Woodham, Omar F. Khan, Jingjing Ling, Daniel G. Anderson, Hidde L. Ploegh
Format: Article
Language:English
Published: Nature Portfolio 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00193-w