Hepatocyte Growth Factor Attenuates the Severity of Status Epilepticus in Kainic Acid-induced Model of Temporal Lobe Epilepsy by Targeting Apoptosis and Astrogliosis

Hepatocyte Growth Factor Attenuates the Severity of Status Epilepticus in Kainic Acid-induced Model of Temporal Lobe Epilepsy by Targeting Apoptosis and Astrogliosis

Introduction: Although pharmacotherapy is the most common treatment for epilepsy, proper seizure control is not achieved with current medications. This study evaluated the protective effects of the Hepatocyte Growth Factor (HGF) in a rat model of Temporal Lobe Epilepsy (TLE) and explored possible mo...

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Bibliographic Details
Main Authors: Sobhan Haghani, Nida Jamali-Raeufy, Motahareh Zeinivand, Soraya Mehrabi, Leila Aryan, Javad Fahanik-Babaei
Format: Article
Language:English
Published: Iran University of Medical Sciences 2021-11-01
Series:Basic and Clinical Neuroscience
Subjects:
hepatocyte growth factor
temporal lobe epilepsy
astrogliosis
apoptosis
memory impairment
Online Access:http://bcn.iums.ac.ir/article-1-1562-en.html

Internet

http://bcn.iums.ac.ir/article-1-1562-en.html

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