Inhibitory Effect of IL-1β on HBV and HDV Replication and HBs Antigen-Dependent Modulation of Its Secretion by Macrophages

Inhibitory Effect of IL-1β on HBV and HDV Replication and HBs Antigen-Dependent Modulation of Its Secretion by Macrophages

Co-infection with the hepatitis B virus and hepatitis delta virus (HDV) leads to the most aggressive form of viral hepatitis. Using in vitro infection models, we confirmed that IL-1β, a crucial innate immune molecule for pathogen control, was very potent against HBV from different genotypes. Additio...

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Bibliographic Details
Main Authors: Marion Delphin, Suzanne Faure-Dupuy, Nathalie Isorce, Michel Rivoire, Anna Salvetti, David Durantel, Julie Lucifora
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
hepatitis D virus
hepatitis B virus
interleukine-1 beta
macrophages
NF-κB
hepatocytes
Online Access:https://www.mdpi.com/1999-4915/14/1/65

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https://www.mdpi.com/1999-4915/14/1/65

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