The mechanical phenotypic plasticity of melanoma cell: an emerging driver of therapy cross-resistance

Abstract Advanced cutaneous melanoma is the deadliest form of skin cancer and one of the most aggressive human cancers. Targeted therapies (TT) against BRAF mutated melanoma and immune checkpoints blockade therapies (ICB) have been a breakthrough in the treatment of metastatic melanoma. However, the...

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Bibliographic Details
Main Authors: Serena Diazzi, Sophie Tartare-Deckert, Marcel Deckert
Format: Article
Language:English
Published: Nature Publishing Group 2023-02-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-023-00452-8