Acute deletion of the central MR/GR steroid receptor correlates with changes in LTP, auditory neural gain, and GC-A cGMP signaling

Acute deletion of the central MR/GR steroid receptor correlates with changes in LTP, auditory neural gain, and GC-A cGMP signaling

The complex mechanism by which stress can affect sensory processes such as hearing is still poorly understood. In a previous study, the mineralocorticoid (MR) and/or glucocorticoid receptor (GR) were deleted in frontal brain regions but not cochlear regions using a CaMKIIα-based tamoxifen-inducible...

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Bibliographic Details
Main Authors: Dila Calis, Morgan Hess, Philine Marchetta, Wibke Singer, Julian Modro, Ellis Nelissen, Jos Prickaerts, Peter Sandner, Robert Lukowski, Peter Ruth, Marlies Knipper, Lukas Rüttiger
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
glucocorticoid receptor
mineralocorticoid receptor
NO-GC
GC-A
cognition
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1017761/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2023.1017761/full

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