Revisiting p38 Mitogen-Activated Protein Kinases (MAPK) in Inflammatory Arthritis: A Narrative of the Emergence of MAPK-Activated Protein Kinase Inhibitors (MK2i)

Revisiting p38 Mitogen-Activated Protein Kinases (MAPK) in Inflammatory Arthritis: A Narrative of the Emergence of MAPK-Activated Protein Kinase Inhibitors (MK2i)

The p38 mitogen-activated protein kinase (p38-MAPK) is a crucial signaling pathway closely involved in several physiological and cellular functions, including cell cycle, apoptosis, gene expression, and responses to stress stimuli. It also plays a central role in inflammation and immunity. Owing to...

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Bibliographic Details
Main Authors: Payal Ganguly, Tom Macleod, Chi Wong, Mark Harland, Dennis McGonagle
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Pharmaceuticals
Subjects:
p38-MAKP pathway
MK2 inhibitor
drug target
inflammation
inflammatory arthritis
Online Access:https://www.mdpi.com/1424-8247/16/9/1286

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https://www.mdpi.com/1424-8247/16/9/1286

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