A drug-delivery depot for epigenetic modulation and enhanced cancer immunotherapy

A drug-delivery depot for epigenetic modulation and enhanced cancer immunotherapy

DNA methyltransferase inhibitors (DNMTis) have found widespread application in the management of cancer. Zebularine (Zeb), functioning as a demethylating agent, has exhibited notable advantages and enhanced therapeutic efficacy in the realm of tumour immunotherapy. Nevertheless, due to its lack of t...

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Bibliographic Details
Main Authors: Junzhong Lai, Jiadi Liang, Yong Zhang, Bingchen Zhang, Jianhui Wei, Jiqiang Fan, Linqin Chen, Zhirong Chen, Qiumei Li, Dong Guo, Jizhen Lin, Qi Chen
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
DNA methyltransferase inhibitors
Zebularine
Chitosan
Cancer treatment
Tumour immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223014853

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http://www.sciencedirect.com/science/article/pii/S0753332223014853

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