A drug-delivery depot for epigenetic modulation and enhanced cancer immunotherapy
DNA methyltransferase inhibitors (DNMTis) have found widespread application in the management of cancer. Zebularine (Zeb), functioning as a demethylating agent, has exhibited notable advantages and enhanced therapeutic efficacy in the realm of tumour immunotherapy. Nevertheless, due to its lack of t...
Main Authors: | Junzhong Lai, Jiadi Liang, Yong Zhang, Bingchen Zhang, Jianhui Wei, Jiqiang Fan, Linqin Chen, Zhirong Chen, Qiumei Li, Dong Guo, Jizhen Lin, Qi Chen |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
|
Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332223014853 |
Similar Items
-
Zebularine, a DNA Methylation Inhibitor, Activates Anthocyanin Accumulation in Grapevine Cells
by: Junhua Kong, et al.
Published: (2022-07-01) -
A Comparative Analysis of 5-Azacytidine- and Zebularine-Induced DNA Demethylation
by: Patrick T. Griffin, et al.
Published: (2016-09-01) -
Epigenetic memory as a basis for intelligent behaviour in clonal plants
by: Vit Latzel, et al.
Published: (2016-08-01) -
Regulation of IFNβ expression: focusing on the role of its promoter and transcription regulators
by: Jiqiang Fan, et al.
Published: (2023-06-01) -
Zebularine and trichostatin A sensitized human breast adenocarcinoma cells towards tumor necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis
by: Wei Yang Kong, et al.
Published: (2019-09-01)