The antiviral activity of a small molecule drug targeting the NSP1-ribosome complex against Omicron, especially in elderly patients

The antiviral activity of a small molecule drug targeting the NSP1-ribosome complex against Omicron, especially in elderly patients

IntroductionWith the emergence of SARS-CoV-2 mutant strains, especially the epidemic of Omicron, it continues to evolve to strengthen immune evasion. Omicron BQ. 1 and XBB pose a serious threat to the current COVID-19 vaccine (including bivalent mRNA vaccine for mutant strains) and COVID-19-positive...

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Bibliographic Details
Main Authors: Min Shen, Ping Ding, Guangxin Luan, Ting Du, Shanshan Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
COVID-19
Nsp1
translational inhibition
elderly patients
Omicron infection
XBB sub-variant
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1141274/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2023.1141274/full

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