Toxoplasma TgAtg8-TgAtg3 Interaction Primarily Contributes to Apicoplast Inheritance and Parasite Growth in Tachyzoite

Toxoplasma TgAtg8-TgAtg3 Interaction Primarily Contributes to Apicoplast Inheritance and Parasite Growth in Tachyzoite

ABSTRACT The apicoplast, which harbors key pathways involved in biosynthesis of vital metabolites, is a unique and essential nonphotosynthetic plastid organelle in apicomplexan parasites. Intriguingly, autophagy-related protein 8 (Atg8), a highly conserved eukaryotic protein, can localize to the out...

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Bibliographic Details
Main Authors: Linyan Cheng, Yuan Tian, Yan Wang, Tingting Wang, Yinning Yao, Helin Yu, Xiaozi Zheng, Mimi Wu, Wei Zhao, Qianqian Hua, Xin Hu, Feng Tan
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:Microbiology Spectrum
Subjects:
Toxoplasma
autophagy
Atg8
Atg3
protein-protein interaction
Atg8-family interacting motif
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01495-21

Internet

https://journals.asm.org/doi/10.1128/spectrum.01495-21

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