Characterization of the monoclonal antibody and the immunodominant B-cell epitope of African swine fever virus pA104R by using mouse model

Characterization of the monoclonal antibody and the immunodominant B-cell epitope of African swine fever virus pA104R by using mouse model

ABSTRACTThe African swine fever virus (ASFV) structural protein pA104R is the only histone-like protein encoded by eukaryotic viruses. pA104R is an essential DNA-binding protein required for DNA replication and genome packaging of ASFV, which are vital for pathogen survival and proliferation. pA104R...

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Bibliographic Details
Main Authors: Qichao Chen, Lixinjie Liu, Shibang Guo, Liang Li, Yifeng Yu, Zhankui Liu, Chen Tan, Huanchun Chen, Xiangru Wang
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:Microbiology Spectrum
Subjects:
African swine fever virus
pA104R
monoclonal antibody
immunodominant B-cell epitope
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01401-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01401-23

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