Forced Overexpression of Signal Transducer and Activator of Transcription 3 (STAT3) Activates Yes-Associated Protein (YAP) Expression and Increases the Invasion and Proliferation Abilities of Small Cell Lung Cancer (SCLC) Cells

Forced Overexpression of Signal Transducer and Activator of Transcription 3 (STAT3) Activates Yes-Associated Protein (YAP) Expression and Increases the Invasion and Proliferation Abilities of Small Cell Lung Cancer (SCLC) Cells

Background: We sought to investigate the interaction between signal transducer and activator of transcription 3 (STAT3) and the Yes-associated protein (YAP) signaling pathway in human small cell lung cancer (SCLC) cells. Methods: The STAT3-overexpressing SCLC cell lines H146 and H446 were establishe...

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Bibliographic Details
Main Authors: Ping-Chih Hsu, Jhy-Ming Li, Cheng-Ta Yang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomedicines
Subjects:
signal transducer and activator of transcription 3 (STAT3)
yes-associated protein (YAP)
Hippo signaling
small cell lung cancer
epithelial–mesenchymal transition (EMT)
proliferation
Online Access:https://www.mdpi.com/2227-9059/10/7/1704

Internet

https://www.mdpi.com/2227-9059/10/7/1704

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