The human Y and inactive X chromosomes similarly modulate autosomal gene expression

The human Y and inactive X chromosomes similarly modulate autosomal gene expression

Summary: Somatic cells of human males and females have 45 chromosomes in common, including the “active” X chromosome. In males the 46th chromosome is a Y; in females it is an “inactive” X (Xi). Through linear modeling of autosomal gene expression in cells from individuals with zero to three Xi and z...

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Bibliographic Details
Main Authors: Adrianna K. San Roman, Helen Skaletsky, Alexander K. Godfrey, Neha V. Bokil, Levi Teitz, Isani Singh, Laura V. Blanton, Daniel W. Bellott, Tatyana Pyntikova, Julian Lange, Natalia Koutseva, Jennifer F. Hughes, Laura Brown, Sidaly Phou, Ashley Buscetta, Paul Kruszka, Nicole Banks, Amalia Dutra, Evgenia Pak, Patricia C. Lasutschinkow, Colleen Keen, Shanlee M. Davis, Angela E. Lin, Nicole R. Tartaglia, Carole Samango-Sprouse, Maximilian Muenke, David C. Page
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Cell Genomics
Subjects:
sex chromosomes
sex differences
X chromosome inactivation
aneuploidy
Turner syndrome
Klinefelter syndrome
Online Access:http://www.sciencedirect.com/science/article/pii/S2666979X23003063

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http://www.sciencedirect.com/science/article/pii/S2666979X23003063

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