Leptospermum extract (QV0) suppresses pleural mesothelioma tumor growth in vitro and in vivo by mitochondrial dysfunction associated apoptosis

Leptospermum extract (QV0) suppresses pleural mesothelioma tumor growth in vitro and in vivo by mitochondrial dysfunction associated apoptosis

Pleural mesothelioma (PM) is a highly aggressive, fast-growing asbestos-induced cancer with limited effective treatments. There has been interest in using naturally occurring anticancer agents derived from plant materials for the treatment of PM. However, it is unclear if an aqueous extract from Lep...

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Bibliographic Details
Main Authors: Huaikai Shi, Le Zhang, Ta-Kun Yu, Ling Zhuang, Helen Ke, Ben Johnson, Emma Rath, Kenneth Lee, Sonja Klebe, Steven Kao, Karl Lijun Qin, Hong Ngoc Thuy Pham, Quan Vuong, Yuen Yee Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Oncology
Subjects:
Leptospermum
mitochondria dysfunction
apoptosis
pleural mesothelioma
anti-cancer (anticancer) drugs
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1162027/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1162027/full

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