Lipopolysaccharide-Induced Strain-Specific Differences in Neuroinflammation and MHC-I Pathway Regulation in the Brains of Bl6 and 129Sv Mice

Lipopolysaccharide-Induced Strain-Specific Differences in Neuroinflammation and MHC-I Pathway Regulation in the Brains of Bl6 and 129Sv Mice

Many studies have demonstrated significant mouse-strain-specific differences in behavior and response to pathogenic and pharmacological agents. This study seeks to characterize possible differences in microglia activation and overall severity of neuroinflammation in two widely used mouse strains, C5...

Full description

Bibliographic Details
Main Authors: Maria Piirsalu, Keerthana Chithanathan, Mohan Jayaram, Tanel Visnapuu, Kersti Lilleväli, Mihkel Zilmer, Eero Vasar
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
lipopolysaccharide
129S6/SvEvTac
C57BL/6NTac
MHC-I
neuroinflammation
innate immunity
Online Access:https://www.mdpi.com/2073-4409/11/6/1032

Internet

https://www.mdpi.com/2073-4409/11/6/1032

Similar Items