Characterization of Toxoplasma gondii glyoxalase 1 and evaluation of inhibitory effects of curcumin on the enzyme and parasite cultures

Characterization of Toxoplasma gondii glyoxalase 1 and evaluation of inhibitory effects of curcumin on the enzyme and parasite cultures

Abstract Background The glyoxalase pathway, which includes two enzymes, glyoxalase 1 and 2 (Glo1 and Glo2), is a ubiquitous cellular system responsible for the removal of cytotoxic methylglyoxal produced during glycolysis. Protozoan parasites, including Toxoplasma gondii (T. gondii) tachyzoites, pro...

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Bibliographic Details
Main Authors: Youn-Kyoung Goo, Junya Yamagishi, Akio Ueno, Mohamad Alaa Terkawi, Gabriel Oluga Aboge, Dongmi Kwak, Yeonchul Hong, Dong-Il Chung, Makoto Igarashi, Yoshifumi Nishikawa, Xuenan Xuan
Format: Article
Language:English
Published: BMC 2015-12-01
Series:Parasites & Vectors
Subjects:
Toxoplasma gondii
Glyoxalase pathway
Curcumin
Online Access:https://doi.org/10.1186/s13071-015-1268-5

Internet

https://doi.org/10.1186/s13071-015-1268-5

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