Peptide-Based siRNA Nanocomplexes Targeting Hepatic Stellate Cells

Peptide-Based siRNA Nanocomplexes Targeting Hepatic Stellate Cells

Liver fibrosis is the excessive accumulation of extracellular matrix (ECM) in the liver due to chronic injuries and inflammation. These injuries activate and transform quiescent hepatic stellate cells (HSCs) into proliferative myofibroblast-like cells, which are the key contributors to the secretin...

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Bibliographic Details
Main Authors: Chien-Yu Lin, Umar-Farouk Mamani, Yuhan Guo, Yanli Liu, Kun Cheng
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomolecules
Subjects:
liver fibrosis
siRNA
nanocomplex
IGF2R
<i>PCBP2</i>
glutamate
Online Access:https://www.mdpi.com/2218-273X/13/3/448

Internet

https://www.mdpi.com/2218-273X/13/3/448

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