5,6-Epoxycholesterol Isomers Induce Oxiapoptophagy in Myeloma Cells

5,6-Epoxycholesterol Isomers Induce Oxiapoptophagy in Myeloma Cells

Multiple myeloma (MM) is an incurable plasma cell malignancy with frequent patient relapse due to innate or acquired drug resistance. Cholesterol metabolism is reported to be altered in MM; therefore, we investigated the potential anti-myeloma activity of two cholesterol derivatives: the 5,6 α- and...

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Bibliographic Details
Main Authors: Oumaima Jaouadi, Inès Limam, Mohamed Abdelkarim, Emna Berred, Ahlem Chahbi, Mélody Caillot, Brigitte Sola, Fatma Ben Aissa-Fennira
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
apoptosis
autophagy
anti-tumor activity
multiple myeloma
oxiapotophagy
oxidative stress
Online Access:https://www.mdpi.com/2072-6694/13/15/3747

Internet

https://www.mdpi.com/2072-6694/13/15/3747

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