COPD Patients Exhibit Distinct Gene Expression, Accelerated Cellular Aging, and Bias to M2 Macrophages

COPD Patients Exhibit Distinct Gene Expression, Accelerated Cellular Aging, and Bias to M2 Macrophages

COPD, one of world’s leading contributors to morbidity and mortality, is characterized by airflow limitation and heterogeneous clinical features. Three main phenotypes are proposed: overlapping asthma/COPD (ACO), exacerbator, and emphysema. Disease severity can be classified as mild, moderate, sever...

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Bibliographic Details
Main Authors: Camila Oliveira da Silva, Jeane de Souza Nogueira, Adriana Paulino do Nascimento, Tatiana Victoni, Thiago Prudente Bártholo, Cláudia Henrique da Costa, Andrea Monte Alto Costa, Samuel dos Santos Valença, Martina Schmidt, Luís Cristóvão Porto
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
COPD
HDAC
telomere
macrophage
Online Access:https://www.mdpi.com/1422-0067/24/12/9913

Internet

https://www.mdpi.com/1422-0067/24/12/9913

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