Immune synergistic mechanism of recombinant plasmid adjuvant containing chicken IL-4 and IL-2 fusion genes on chicken coccidia live vaccine

Immune synergistic mechanism of recombinant plasmid adjuvant containing chicken IL-4 and IL-2 fusion genes on chicken coccidia live vaccine

ABSTRACT: The recombinant plasmid pCI-IL-4-IL-2-EGFP containing fusion genes of chicken IL-4 and IL-2 can be used as an adjuvant to enhance the anticoccidiosis effect of the chicken coccidia live vaccine. The chickens were divided into 3 groups: blank control group, vaccine + pCI-IL-4-IL-2-EGFP adju...

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Bibliographic Details
Main Authors: Fan Tan, Li Zhang, Liyang Yin, Liming Wang, Honghui Zhang, Longlong Zheng, Xiaozhen Cui, Xiaoling Lv, Rui Bai, Mingxue Zheng
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Poultry Science
Subjects:
pCI-IL-4-IL-2-EGFP adjuvant
chicken coccidia live vaccine
cytokine
lymphocyte
antigen presenting cell
Online Access:http://www.sciencedirect.com/science/article/pii/S003257912300723X

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http://www.sciencedirect.com/science/article/pii/S003257912300723X

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