Anti-Parkinsonian effect of Mucuna pruriens and Ursolic acid on GSK3β/Calcium signaling in neuroprotection against Rotenone-induced Parkinsonism

Anti-Parkinsonian effect of Mucuna pruriens and Ursolic acid on GSK3β/Calcium signaling in neuroprotection against Rotenone-induced Parkinsonism

Background: Exposure of environmental toxin is linked to the onset of Parkinson's disease (PD), especially in majority of sporadic cases. One of such toxins, namely Rotenone has been widely investigated to produce the Parkinsonian model in laboratories. The toxin causes the death of the dopamin...

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Bibliographic Details
Main Authors: Walia Zahra, Hareram Birla, Saumitra Sen Singh, Aaina Singh Rathore, Hagera Dilnashin, Richa Singh, Priyanka Kumari Keshri, Shekhar Singh, Surya Pratap Singh
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Phytomedicine Plus
Subjects:
Parkinson’ disease
Ca2+ level
GSK-3β
Rotenone
Mucuna pruriens
Ursolic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031322001245

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http://www.sciencedirect.com/science/article/pii/S2667031322001245

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