Cancer Stem Cells, Bone and Tumor Microenvironment: Key Players in Bone Metastases
Tumor mass is constituted by a heterogeneous group of cells, among which a key role is played by the cancer stem cells (CSCs), possessing high regenerative properties. CSCs directly metastasize to bone, since bone microenvironment represents a fertile environment that protects CSCs against the immun...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-02-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/10/2/56 |