Establishment of induced pluripotent stem cell lines derived from Parkinson’s disease Mexican patients: A sporadic (UNAMi002-A) and a familial (UNAMi003-A) case carrying a mutation in PINK1

Establishment of induced pluripotent stem cell lines derived from Parkinson’s disease Mexican patients: A sporadic (UNAMi002-A) and a familial (UNAMi003-A) case carrying a mutation in PINK1

Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta, which results in a prominent reduction of striatal dopamine levels leading to motor alterations. The mechanisms underlying neurodegeneration in PD remain unknown. Here, we...

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Bibliographic Details
Main Authors: Xóchitl Flores-Ponce, Adolfo López-Ornelas, Itzel Escobedo-Avila, Mayela Rodríguez-Violante, David Dávila-Ortiz de Montellano, Amín Cervantes-Arriaga, Nancy Monroy-Jaramillo, Aurelio Campos-Romo, Iván Velasco
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506124000357

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http://www.sciencedirect.com/science/article/pii/S1873506124000357

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