Establishment of induced pluripotent stem cell lines derived from Parkinson’s disease Mexican patients: A sporadic (UNAMi002-A) and a familial (UNAMi003-A) case carrying a mutation in PINK1
Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta, which results in a prominent reduction of striatal dopamine levels leading to motor alterations. The mechanisms underlying neurodegeneration in PD remain unknown. Here, we...
| Main Authors: | , , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Elsevier
2024-04-01
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| 丛编: | Stem Cell Research |
| 在线阅读: | http://www.sciencedirect.com/science/article/pii/S1873506124000357 |