In silico prediction of inhibition of promiscuous breast cancer resistance protein (BCRP/ABCG2).

Breast cancer resistant protein has an essential role in active transport of endogenous substances and xenobiotics across extracellular and intracellular membranes along with P-glycoprotein. It also plays a major role in multiple drug resistance and permeation of blood-brain barrier. Therefore, it i...

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Bibliographic Details
Main Authors: Yi-Lung Ding, Yu-Hsuan Shih, Fu-Yuan Tsai, Max K Leong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3948701?pdf=render