Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model

Dravet syndrome is a catastrophic epilepsy of childhood, characterized by cognitive impairment, severe seizures, and increased risk for sudden unexplained death in epilepsy (SUDEP). Although refractory to conventional antiepileptic drugs, emerging preclinical and clinical evidence suggests that modu...

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Bibliographic Details
Main Authors: Aliesha Griffin, Mana Anvar, Kyla Hamling, Scott C. Baraban
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00464/full