Chromatographic lipophilicity as a predictor of antiproliferative activity of 17-picolyl and 17-picolinylidene androstane derivatives toward prostate cancer

Chromatographic lipophilicity as a predictor of antiproliferative activity of 17-picolyl and 17-picolinylidene androstane derivatives toward prostate cancer

The present study describes the quantitative retention - (anticancer) activity relationship analysis of a series of 17-picolyl and 17-picolinylidene androstane derivatives based on the chromatographic data obtained by reversed-phase high performance liquid chromatography (C18-RP-HPLC) in...

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Bibliographic Details
Main Authors: Kovačević Strahinja Z., Podunavac-Kuzmanović Sanja O., Jevrić Lidija R., Đurendić Evgenija A., Ajduković Jovana J., Jovanov Pavle T.
Format: Article
Language:English
Published: Faculty of Technology, Novi Sad 2015-01-01
Series:Acta Periodica Technologica
Subjects:
Prostate cancer
chemometrics
chromatography
lipophilicity
molecular modeling
Online Access:http://www.doiserbia.nb.rs/img/doi/1450-7188/2015/1450-71881546239K.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/1450-7188/2015/1450-71881546239K.pdf

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