Spatiotemporal evolution of blood brain barrier damage and tissue infarction within the first 3 h after ischemia onset

Blood brain barrier (BBB) damage that occurs within the thrombolytic time window is increasingly appreciated to negatively impact the safety and efficacy profiles of thrombolytic therapy for ischemic stroke. However, the spatiotemporal evolution of BBB damage in this early stroke stage and the under...

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Bibliographic Details
Main Authors: Xinchun Jin, Jie Liu, Yi Yang, Ke J. Liu, Yirong Yang, Wenlan Liu
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996112002483