Peptide 19-2.5 inhibits heparan sulfate-triggered inflammation in murine cardiomyocytes stimulated with human sepsis serum.

Peptide 19-2.5 inhibits heparan sulfate-triggered inflammation in murine cardiomyocytes stimulated with human sepsis serum.

Myocardial dysfunction in sepsis has been linked to inflammation caused by pathogen-associated molecular patterns (PAMPs) as well as by host danger-associated molecular patterns (DAMPs). These include soluble heparan sulfate (HS), which triggers the devastating consequences of the pro-inflammatory c...

Full description

Bibliographic Details
Main Authors: Lukas Martin, Susanne Schmitz, Rebecca De Santis, Sabine Doemming, Hajo Haase, Janine Hoeger, Lena Heinbockel, Klaus Brandenburg, Gernot Marx, Tobias Schuerholz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4449035?pdf=render

Internet

http://europepmc.org/articles/PMC4449035?pdf=render

Similar Items