Activation of oligodendroglial Stat3 is required for efficient remyelination

Multiple sclerosis is the most prevalent demyelinating disease of the central nervous system (CNS) and is histologically characterized by perivascular demyelination as well as neurodegeneration. While the degree of axonal damage is correlated with clinical disability, it is believed that remyelinati...

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Bibliographic Details
Main Authors: Andrew J. Steelman, Yun Zhou, Hisami Koito, SunJa Kim, H. Ross Payne, Q. Richard Lu, Jianrong Li
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996116300699