Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans

Epigenome-wide association study identifies DNA methylation sites associated with target organ damage in older African Americans

Target organ damage (TOD) manifests as vascular injuries in the body organ systems associated with long-standing hypertension. DNA methylation in peripheral blood leukocytes can capture inflammatory processes and gene expression changes underlying TOD. We investigated the association between epigeno...

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Bibliographic Details
Main Authors: Farah Ammous, Wei Zhao, Scott M. Ratliff, Minjung Kho, Lulu Shang, Alana C. Jones, Ninad S. Chaudhary, Hemant K. Tiwari, Marguerite R. Irvin, Donna K. Arnett, Thomas H. Mosley, Lawrence F. Bielak, Sharon L.R. Kardia, Xiang Zhou, Jennifer Smith
Format: Article
Language:English
Published: Taylor & Francis Group 2021-08-01
Series:Epigenetics
Subjects:
target organ damage
dna methylation
estimated glomerular filtration rate
urinary albumin-creatinine ratio
left ventricular mass
relative wall thickness
Online Access:http://dx.doi.org/10.1080/15592294.2020.1827717

Internet

http://dx.doi.org/10.1080/15592294.2020.1827717

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