Negative Correlation Between 18F-RGD Uptake via PET and Tumoral PD-L1 Expression in Non-Small Cell Lung Cancer

Negative Correlation Between 18F-RGD Uptake via PET and Tumoral PD-L1 Expression in Non-Small Cell Lung Cancer

PurposeWe investigated the correlation of 18F-AlF-NOTAPRGD2 (18F-RGD) uptake during positron emission tomography (PET) with tumoral programmed death-ligand 1 (PD-L1) expression and explored its potential in immune checkpoint inhibitor treatment.MethodsForty-two mice were subcutaneously injected with...

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Bibliographic Details
Main Authors: Leilei Wu, Jingru Liu, Shasha Wang, Menglin Bai, Min Wu, Zhenhua Gao, Jianing Li, Jinming Yu, Jie Liu, Xue Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Endocrinology
Subjects:
18 F-RGD PET
negative correlation
tumoral PD-L1 expression
SUVmax
non-small cell lung cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.913631/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.913631/full

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