Immunological Significance of HMGB1 Post-Translational Modification and Redox Biology

Immunological Significance of HMGB1 Post-Translational Modification and Redox Biology

Most extracellular proteins are secreted via the classical endoplasmic reticulum (ER)/Golgi-dependent secretion pathway; however, some proteins, including a few danger-associated molecular patterns (DAMPs), are secreted via non-classical ER/Golgi-independent secretion pathways. The evolutionarily co...

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Bibliographic Details
Main Authors: Man Sup Kwak, Hee Sue Kim, Bin Lee, Young Hun Kim, Myoungsun Son, Jeon-Soo Shin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
high mobility group box1 (HMGB1)
oxidation
inflammation
therapeutic target
danger-associated molecular pattern (DAMP)
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01189/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.01189/full

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